Sam and Dean exit the building, when all of a sudden more red lightning bolts strike the ground. Sam is shown very unhappy with the loss, even more when a handful of other hunters have been killed in a short period of time.
Lucifer attempts to use the Hand of God to kill Sam and Dean, but its power has been used up, and it fails. Later, Sam and Dean return to the Bunker, Dean having told Sam about the baby Amara 's disappearance, and how Dean suspects that she is the Darkness, even though she is a baby.
After speaking with Father Simon, they go back to the Bunker and watch the reel of the last test, in which Father Thompson successfully cures a demon after injecting it with his blood several, which had been purified through confession. The narrative picks up in 11.
Castiel tells Sam that keeping this a secret from Dean is a bad idea, but Sam knows that Dean wouldn't approve, and that he would try to stop them. Sam pretends to be a doctor in 10.
Sam and Dean return to the police station to track the missing deputy, and reports begin flooding in that the fog is on its way to overtake the town. When they finally have everything they need, however, Dean doesn't answer is phone, and when Rowena tells Sam that it's now or never, they leave to go to Hell without Dean.
It's a fairly common fear for someone to have, which may be surprising, given that his work as a hunter means that Sam isn't afraid of any of the usual ghosts, vampires, demons, or other monsters that people might find to be a source of terror.
Sam's speech to Mick was reminiscence of his speech to Max Miller and Magda Peterson , in which he urged both not to kill someone. Once, however, Sam took the liberty of actually changing something about the Impala to bring it a little bit up to date... That adds up to one death, and technically three more resurrections.
Even in childhood, the two occasionally struggled with having to look after each other, but now that they are adults, Sam and Dean would do anything to save their brother - even fighting with Gods, demons, and death itself. Sam believes that Dean never went back to Lisa after the Apocalypse was stopped, and when Dean tells him briefly that after a year, his relationship with Lisa did not work out, Sam is sympathetic.Supernatural - Jessica's Death
She tells them where she is, and that there is someone trying to break in. While Sam and Dean are talking with the Publisher of the Supernatural series, she mentions that she found Sam's decision to shoot Madison - "the first woman since Jessica he ever loved" - to be a particularly moving part of the series.
In fact, his telekinesis did not manifest again until after he began training with Ruby and drinking her blood.
Sam then kills Samuel this time possessed by the Khan Worm in episode 16 of season six '... Sam and Rowena briefly bond over their shared trauma of seeing Lucifer's true face.
Sam is ready with the holy water, and splashes it in his face as he quickly injects the blood into Dean's arm. Although she breaks up with him when she begins dating Chuck , Sam pretends to be hurt by it but is actually relieved.